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Oxford HBV Decision Trees



RULES:
Rule 1: Subtype Assigned
Subtype assigned based on sequence > 800 bps, clustering with a pure subtype with bootstrap > 70% without recombination in the bootscan.

Rule 2: check the bootscan
Subtype unassigned based on sequence > 800bp, clustering with a pure subtype with bootstrap >70 %, with detection of recombination in the pure subtype bootscan.


Rule 3: check the report
Subtype unassigned based on sequence > 800bp, do not clustering with a pure subtype with bootstrap >70 %, with no detection of recombination in the pure subtype bootscan.

Rule 4: check the bootscan
Subtype unassigned based on sequence > 800bp, do not clustering with a pure subtype with bootstrap > 70 %, with detection of recombination in the pure subtype bootscan.


Rule 5: Pure
Subtype assigned based on sequence < 800bp, clustering with inside a HBV subtype with bootstrap > 70%.

Rule 5: check the report
Subtype assigned based on sequence < 800bp, clustering with outside a HBV subtype with bootstrap > 70%.

Rule 6: check the report
Subtype unassigned based on sequence < 800bp, do not clustering with a pure subtype with bootstrap >70 %.

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Developed by: Tulio de Oliveira, Sharon Cassol, Emmanouil Magiorkinis, Dimitrios Paraskevis and Andrew Rambaut

Developed in cooperation with the Evolutionary Biology Group at University of Oxford, UK and the the HIV-1 Pathogenesis and Immunotherapeutics Program at University of Pretoria, South Africa.

Funded by the Marie Curie Fellowship, Wellcome Trust and Royal Society, UK.

Suggestions or problems on the program please contact:  Dr Tulio de Oliveira.